Association of anti-phospholipid antibodies with connective tissue diseases

[Serum anti endomysial and anti transglutaminase antibodies in patients with connective tissue diseases].

BACKGROUND The detection of anti-transglutaminase IgA (tTG) and anti-endomysial (EMA) is used for screening of celiac disease (CD) with a sensitivity and specificity of 90 and 99% respectively. There is an association between CD and connective tissue diseases (CTD). AIM To report the frequency of IgA tTG and EMA in patients with a definite diagnosis of CTD and inflammatory arthropathies (IA)....

Anti-endothelial cell antibodies in mixed connective tissue disease: frequency and association with clinical symptoms.

OBJECTIVE Anti-endothelial cell antibodies (AECA) have been described in a number of systemic autoimmune-inflammatory diseases. However, little is known about the relationship of AECA with mixed connective tissue disease (MCTD). METHODS Using an ELISA, the presence of AECA was evaluated in the sera of 33 patients with MCTD and of 30 healthy subjects as controls. Serum levels of AECA were corr...

Urticarial vasculitis and syndromes in association with connective tissue diseases.

Anti-Ro52 Antibodies and Interstitial Lung Disease in Connective Tissue Diseases Excluding Scleroderma

Introduction. The presence of anti-Ro52 antibodies has been reported in a wide variety of autoimmune diseases, particularly in myositis, scleroderma, and autoimmune liver diseases. Clinical significance of anti-Ro52 antibodies remains controversial, and studies are lacking for clarifying the association of anti-Ro52 with interstitial lung disease (ILD) in connective tissue diseases (CTD). Objec...

Precipitating auto-antibodies in the connective tissue diseases.

In a recent communication we described the occurrence in the serum of patients with Sjogren's disease of two factors which reacted to give precipitates with extracts of various tissues. Evidence was provided that both factors were auto-antibodies (Anderson, Gray, Beck, and Kinnear, 1961b). As Sjogren's disease has close associations with the connective tissue diseases (Heaton, 1959; Bunim, 1961...